产品货号：
Z23606
中文名称：
PHLPP/PHLPP1抗体
英文名称：
Anti-PHLPP/PHLPP1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PHLPP/PHLPP1 Antibody |
| 指标别名 | hSCOP;KIAA0606;PHLPP;PHLPP1;PLEKHE1;SCOP |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | PHLPP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PHLPP1 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PHLPP1.The immunogen is located within amino acids 250 - 300 of PHLPP1. |
| 计算分子量 | 185kDa |
| 成分 | PHLPP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PHLPP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | PHLPP1 is a member of the serine/threonine phosphatase family,which are important regulators of Akt serine-threonine kinases (AKT1,AKT2,AKT3) and conventional/novel protein kinase C (PKC) isoforms.PHLPP1 and PHLPP2 have a similar domain structure and have been shown to dephosphorylate and inactivate,distinct Akt isoforms,at one of the two critical phosphorylation sites required for activation:Serine473.PHLPP2 dephosphorylates AKT1 and AKT3,whereas PHLPP1 is specific for AKT2 and AKT3.PHLPP1 promotes apoptosis and may act as a tumor suppressor.Increased expression of PHLPP1 may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. |
| Uniprot ID | O60346 |
| 基因名全称 | PH domain and leucine rich repeat protein phosphatase 1 |
| 蛋白名全称 | PH domain and leucine rich repeat protein phosphatase 1 |
| 推荐稀释比 | PHLPP1 antibody can be used for detection of PHLPP1 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索：PHLPP/PHLPP1抗体，PHLPP抗体，PHLPP1多抗，Anti-PHLPP/PHLPP1 Antibody